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MDM2 抗体 (AA 130-230)

MDM2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3020951
发货至: 中国
  • 抗原 See all MDM2 抗体
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    抗原表位
    • 26
    • 25
    • 14
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 130-230
    适用
    • 195
    • 80
    • 55
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 170
    • 28
    • 1
    克隆类型
    • 170
    • 29
    多克隆
    标记
    • 100
    • 13
    • 9
    • 9
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDM2 antibody is un-conjugated
    应用范围
    • 126
    • 77
    • 64
    • 38
    • 29
    • 27
    • 27
    • 18
    • 18
    • 14
    • 10
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    ENRCHLEGGS DQKDLVQELQ EEKPSSSHLV SRPSTSSRRR AISETEENSD ELSGERQRKR HKSDSISLSF DESLALCVIR EICCERSSSS ESTGTPSNPD L
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 130-230 of human MDM2 (NP_002383.2).
    亚型
    IgG
    Top Product
    Discover our top product MDM2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    别名
    MDM2 (MDM2 产品)
    别名
    ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
    背景
    This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.,MDM2,ACTFS,HDMX,hdm2,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G2/M DNA Damage Checkpoint,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,Neuroscience,MDM2
    分子量
    11-14 kDa/24-55 kDa
    基因ID
    4193
    UniProt
    Q00987
    途径
    p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
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