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LRP5 抗体 (AA 1000-1250)

LRP5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1513164
发货至: 中国
  • 抗原 See all LRP5 抗体
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    抗原表位
    • 17
    • 15
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1000-1250
    适用
    • 59
    • 45
    • 22
    • 1
    • 1
    宿主
    • 67
    • 5
    • 1
    • 1
    克隆类型
    • 70
    • 4
    多克隆
    标记
    • 26
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This LRP5 antibody is un-conjugated
    应用范围
    • 43
    • 38
    • 26
    • 20
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    IKRAKDDGTQ PFVLTSLSQG QNPDRQPHDL SIDIYSRTLF WTCEATNTIN VHRLSGEAMG VVLRGDRDKP RAIVVNAERG YLYFTNMQDR AAKIERAALD GTEREVLFTT GLIRPVALVV DNTLGKLFWV DADLKRIESC DLSGANRLTL EDANIVQPLG LTILGKHLYW IDRQQQMIER VEKTTGDKRT RIQGRVAHLT GIHAVEEVSL EEFSAHPCAR DNGGCSHICI AKGDGTPRCS CPVHLVLLQN L
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Fu, Wang, Wan, Lin, Chang, Han: "Wnt5a mediated canonical Wnt signaling pathway activation in orthodontic tooth movement: possible role in the tension force-induced bone formation." in: Journal of molecular histology, Vol. 47, Issue 5, pp. 455-66, (2017) (PubMed).

  • 抗原
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    别名
    LRP5 (LRP5 产品)
    别名
    Xlrp5 antibody, bmnd1 antibody, evr1 antibody, evr4 antibody, hbm antibody, lr3 antibody, lrp5-A antibody, lrp7 antibody, oppg antibody, ops antibody, opta1 antibody, vbch2 antibody, LRP5 antibody, LRP6 antibody, BMND1 antibody, EVR1 antibody, EVR4 antibody, HBM antibody, LR3 antibody, LRP7 antibody, OPPG antibody, OPS antibody, OPTA1 antibody, VBCH2 antibody, mKIAA4142 antibody, low-density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 antibody, LDL receptor related protein 5 L homeolog antibody, low density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 like antibody, LOC100147353 antibody, LRP5 antibody, lrp5.L antibody, lrp5 antibody, Lrp5 antibody, LRP5L antibody
    背景
    This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.,LRP5,BMND1,EVR1,EVR4,HBM,LR3,LRP-5,LRP7,OPPG,OPS,OPTA1,VBCH2,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Extracellular Matrix,Bone,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Stem Cells,Cardiovascular,Lipids,LRP5
    分子量
    179 kDa
    基因ID
    4041
    UniProt
    O75197
    途径
    WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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