PDPK1 抗体 (pSer241)
(1 reference)-
- 抗原 See all PDPK1 抗体
- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
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抗原表位
- pSer241
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDPK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Phosphorylated Antibodies
- 免疫原
- A phospho specific peptide corresponding to residues surrounding S241 of human PDK1/PDPK1
- 亚型
- IgG
- Top Product
- Discover our top product PDPK1 Primary Antibody
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anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (pSer241) antibody
PDPK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 150-429) antibodyPDPK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 1-429) antibodyPDPK1 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 1-150) antibodyPDPK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 457-556) antibodyPDPK1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7E4G11 unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibodyPDPK1 适用: 人, 大鼠, 猴 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4A11 unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 524-556), (C-Term) antibodyPDPK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 83-338) antibodyPDPK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 457-556) antibodyPDPK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (Internal Region) antibodyPDPK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis." in: Molecular cell, Vol. 71, Issue 2, pp. 201-215.e7, (2018) (PubMed).
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: "Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis." in: Molecular cell, Vol. 71, Issue 2, pp. 201-215.e7, (2018) (PubMed).
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- 抗原
- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
- 别名
- PDPK1 (PDPK1 产品)
- 别名
- pdpk1 antibody, MGC82080 antibody, PDK1 antibody, PDPK2 antibody, PRO0461 antibody, Pdk1 antibody, zgc:153787 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 antibody, ATPDK1 antibody, AtPDK1 antibody, T32M21.110 antibody, T32M21_110 antibody, zgc:77318 antibody, 3-phosphoinositide dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1 L homeolog antibody, 3-phosphoinositide dependent protein kinase-1 antibody, 3-phosphoinositide dependent protein kinase 1a antibody, 3-phosphoinositide-dependent protein kinase 1 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1b antibody, PDPK1 antibody, pdpk1.L antibody, pdpk1 antibody, Pdpk1 antibody, pdpk1a antibody, LOC100380750 antibody, pdk-1 antibody, PDK1 antibody, pdpk1b antibody
- 背景
- Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling . Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses. Provides negative feedback inhibition to toll-like receptor-mediated NF-kappa-B activation in macrophages. Isoform 3 is catalytically inactive.,PDPK1,PDK1,PDPK2,PDPK2P,PRO0461,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cytoskeleton,Microfilaments,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Neuroscience,Protein phosphorylation,PDPK1
- 分子量
- 48 kDa/50 kDa/58 kDa/60 kDa/63 kDa
- 基因ID
- 5170
- UniProt
- O15530
- 途径
- PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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