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Cyclin E1 抗体 (pThr395)

CCNE1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3019435
发货至: 中国
  • 抗原 See all Cyclin E1 (CCNE1) 抗体
    Cyclin E1 (CCNE1)
    抗原表位
    • 27
    • 16
    • 15
    • 13
    • 9
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    • 7
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    • 3
    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pThr395
    适用
    • 147
    • 38
    • 34
    • 3
    • 2
    • 2
    • 2
    宿主
    • 123
    • 23
    • 1
    克隆类型
    • 114
    • 33
    多克隆
    标记
    • 82
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Cyclin E1 antibody is un-conjugated
    应用范围
    • 103
    • 48
    • 47
    • 42
    • 35
    • 28
    • 22
    • 13
    • 13
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    LLTPP
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Phosphorylated Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic phosphorylated peptide around T395 of human Cyclin E1 (NP_001229.1).
    亚型
    IgG
    Top Product
    Discover our top product CCNE1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Cyclin E1 (CCNE1)
    别名
    CCNE1 (CCNE1 产品)
    别名
    CCNE1 antibody, ccne antibody, cyclinE antibody, CCNE antibody, AW538188 antibody, CycE1 antibody, CYCLE antibody, Ccne antibody, cyce2 antibody, cycE3 antibody, cyce antibody, fa18e07 antibody, wu:fa18e07 antibody, cyclin E1 antibody, cyclin E1 L homeolog antibody, cyclin E1 S homeolog antibody, CCNE1 antibody, ccne1 antibody, Ccne1 antibody, ccne1.L antibody, ccne1.S antibody
    背景
    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB.,CCNE1,CCNE,pCCNE1,cyclin E1,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G1/S Checkpoint,Hedgehog Signaling Pathway,Protein phosphorylation,CCNE1
    分子量
    41 kDa/45 kDa/47 kDa
    基因ID
    898
    UniProt
    P24864
    途径
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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