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TERT 抗体 (C-Term)

TERT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3017112
发货至: 中国
  • 抗原 See all TERT 抗体
    TERT (Telomerase Reverse Transcriptase (TERT))
    抗原表位
    • 16
    • 16
    • 10
    • 10
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 105
    • 38
    • 20
    • 5
    • 1
    • 1
    宿主
    • 107
    • 6
    • 1
    克隆类型
    • 99
    • 15
    多克隆
    标记
    • 59
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TERT antibody is un-conjugated
    应用范围
    • 74
    • 55
    • 39
    • 27
    • 17
    • 16
    • 16
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    NIYKILLLQA YRFHACVLQL PFHQQVWKNP TFFLRVISDT ASLCYSILKA KNAGMSLGAK GAAGPLPSEA VQWLCHQAFL LKLTRHRVTY VPLLGSLRTA QTQLSRKLPG TTLTALEAAA NPALPSDFKT ILD
    交叉反应
    人, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 1000 to the C-terminus of human TERT (NP_937983.2).
    亚型
    IgG
    Top Product
    Discover our top product TERT Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TERT (Telomerase Reverse Transcriptase (TERT))
    别名
    TERT (TERT 产品)
    背景
    Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.,TERT,CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT,hEST2,hTRT,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,TERT
    分子量
    88 kDa/90 kDa/120 kDa/126 kDa
    基因ID
    7015
    UniProt
    O14746
    途径
    Telomere Maintenance
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