ATG4C 抗体 (N-Term) (HRP)
-
- 抗原 See all ATG4C 抗体
- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
-
抗原表位
- N-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ATG4C antibody is conjugated to HRP
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Predicted molecular weight at ~52.5 kDa. Observed molecular weights at ~45-60 kDa.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Peptide Affinity Purified
- 免疫原
- Synthetic peptide from the N-terminal of human ATG4C
- Top Product
- Discover our top product ATG4C Primary Antibody
-
-
- 应用备注
-
- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
-
A 1:1000 dilution of ABIN2868967 was sufficient for detection of ATG4C on HeLa cell lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
-
- 抗原
- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
- 别名
- ATG4C (ATG4C 产品)
- 别名
- apg4c antibody, atg4cl antibody, zgc:86888 antibody, wu:fc56g07 antibody, APG4-C antibody, APG4C antibody, AUTL1 antibody, AUTL3 antibody, Apg4-C antibody, Apg4c antibody, Atg4cl antibody, Autl1 antibody, autophagy related 4C cysteine peptidase antibody, autophagy related 4C, cysteine peptidase antibody, cysteine protease ATG4C antibody, ATG4C antibody, atg4c antibody, Tsp_15996 antibody, Atg4c antibody
- 背景
- ATG4C belongs to the peptidase C54 family. It is a cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It also has an activity of delipidating enzyme for the PE-conjugated forms (1).
- 基因ID
- 84938
- NCBI登录号
- NP_116241
- UniProt
- Q96DT6
- 途径
- Autophagy
-