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ATG4C 抗体 (N-Term) (APC)

ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal APC
产品编号 ABIN2868964
发货至: 中国
  • 抗原 See all ATG4C 抗体
    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
    抗原表位
    • 15
    • 15
    • 11
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 66
    • 30
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 59
    • 11
    • 2
    • 1
    克隆类型
    • 63
    • 10
    多克隆
    标记
    • 31
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG4C antibody is conjugated to APC
    应用范围
    • 67
    • 28
    • 23
    • 23
    • 13
    • 13
    • 13
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Predicted molecular weight at ~52.5 kDa. Observed molecular weights at ~45-60 kDa.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Peptide Affinity Purified
    免疫原
    Synthetic peptide from the N-terminal of human ATG4C
    Top Product
    Discover our top product ATG4C Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    A 1:1000 dilution of ABIN2868964 was sufficient for detection of ATG4C on HeLa cell lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
    别名
    ATG4C (ATG4C 产品)
    别名
    apg4c antibody, atg4cl antibody, zgc:86888 antibody, wu:fc56g07 antibody, APG4-C antibody, APG4C antibody, AUTL1 antibody, AUTL3 antibody, Apg4-C antibody, Apg4c antibody, Atg4cl antibody, Autl1 antibody, autophagy related 4C cysteine peptidase antibody, autophagy related 4C, cysteine peptidase antibody, cysteine protease ATG4C antibody, ATG4C antibody, atg4c antibody, Tsp_15996 antibody, Atg4c antibody
    背景
    ATG4C belongs to the peptidase C54 family. It is a cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It also has an activity of delipidating enzyme for the PE-conjugated forms (1).
    基因ID
    84938
    NCBI登录号
    NP_116241
    UniProt
    Q96DT6
    途径
    Autophagy
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