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DUSP6 抗体

DUSP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856801
发货至: 中国
  • 抗原 See all DUSP6 抗体
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This DUSP6 antibody is un-conjugated
    应用范围
    • 64
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    Western Blotting (WB)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to DUSP6 (dual specificity phosphatase 6)
    DUSP6 antibody [N2C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human DUSP6. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product DUSP6 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse liver , HepG2 , rat liver

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    别名
    dual specificity phosphatase 6 (DUSP6 产品)
    别名
    HH19 antibody, MKP3 antibody, PYST1 antibody, 1300019I03Rik antibody, MKP-3 antibody, Mkp3 antibody, wu:fd99d09 antibody, mkp3 antibody, pyst1 antibody, DUSP6 antibody, dusp6 antibody, dual specificity phosphatase 6 antibody, dual specificity phosphatase 6 L homeolog antibody, Dual specificity protein phosphatase 6 antibody, DUSP6 antibody, Dusp6 antibody, dusp6 antibody, dusp6.L antibody, dus6 antibody
    背景
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Cytoplasm
    分子量
    42 kDa
    基因ID
    1848
    UniProt
    Q16828
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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