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Coagulation Factor X 抗体

F10 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856706
发货至: 中国
  • 抗原 See all Coagulation Factor X (F10) 抗体
    Coagulation Factor X (F10)
    适用
    • 62
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    宿主
    • 48
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    克隆类型
    • 61
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    多克隆
    标记
    • 46
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    This Coagulation Factor X antibody is un-conjugated
    应用范围
    • 40
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 大鼠
    产品特性
    Rabbit Polyclonal antibody to Factor X (coagulation factor X)
    Factor X antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Factor X. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product F10 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: human F10-transfected 293T cells , rat liver

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Coagulation Factor X (F10)
    别名
    coagulation factor X (F10 产品)
    别名
    FX antibody, FXA antibody, Cf10 antibody, fX antibody, fi12c10 antibody, wu:fi12c10 antibody, F10 antibody, f10 antibody, coagulation factor X antibody, Coagulation factor X antibody, coagulation factor 10 L homeolog antibody, F10 antibody, f10 antibody, CpipJ_CPIJ012712 antibody, CpipJ_CPIJ014863 antibody, CpipJ_CPIJ016937 antibody, CpipJ_CPIJ017791 antibody, fa10 antibody, f10.L antibody
    背景
    This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

    Cellular Localization: Secreted
    分子量
    55 kDa
    基因ID
    2159
    UniProt
    P00742
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