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- 抗原 See all AXIN2 抗体
- AXIN2 (Axin 2 (AXIN2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AXIN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit polyclonal antibody to axin 2 (axin 2 (conductin, axil))
axin 2 antibody [N2C2], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Axin 2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product AXIN2 Primary Antibody
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anti-Axin 2 (AXIN2) (AA 650-750) antibody
AXIN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843) antibodyAXIN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 56-73) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) antibodyAXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 331-430) antibodyAXIN2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 350-631) antibodyAXIN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 11-77) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 420-520) antibody (HRP)AXIN2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal HRP
anti-Axin 2 (AXIN2) (AA 420-520) antibody (FITC)AXIN2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal FITC
anti-Axin 2 (AXIN2) (AA 200-300) antibody (Alkaline Phosphatase (AP))AXIN2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
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- 应用备注
- IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- AXIN2 (Axin 2 (AXIN2))
- 别名
- axin 2 (AXIN2 产品)
- 别名
- AXIL antibody, ODCRCS antibody, axil antibody, wu:fb37c08 antibody, zgc:111942 antibody, axin-2 antibody, xarp antibody, MGC81576 antibody, arp-A antibody, axin2 antibody, Axi1 antibody, Axil antibody, Conductin antibody, axin 2 antibody, axin 2 (conductin, axil) antibody, axin 2 (conductin, axil) S homeolog antibody, AXIN2 antibody, axin2 antibody, axin2.S antibody, Axin2 antibody
- 背景
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The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
Cellular Localization: Cytoplasm - 分子量
- 94 kDa
- 基因ID
- 8313
- UniProt
- Q9Y2T1
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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