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PSMC5 抗体 (Center)

PSMC5 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856087
发货至: 中国
  • 抗原 See all PSMC5 抗体
    PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))
    抗原表位
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 28
    • 19
    • 18
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 22
    • 5
    • 1
    克隆类型
    • 21
    • 7
    多克隆
    标记
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMC5 antibody is un-conjugated
    应用范围
    • 17
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    斑马鱼, 非洲爪蟾, Xenopus tropicalis, 猕猴, Chimpanzee, 牛
    交叉反应 (详细)
    Zebrafish (100 %), Xenopus laevis (100 %), Xenopus Tropicalis (100 %), Rhesus Monkey (100 %), Chimpanzee (100 %), Bovine (100 %)
    产品特性
    Rabbit Polyclonal antibody to PSMC5 (proteasome (prosome, macropain) 26S subunit, ATPase, 5)
    PSMC5 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human PSMC5. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PSMC5 Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: A431 , HepG2 , Neuro2A , GL261 , C8D30 , PC-12

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))
    别名
    PSMC5 (PSMC5 产品)
    别名
    mSUG1 antibody, S8 antibody, SUG-1 antibody, SUG1 antibody, TBP10 antibody, TRIP1 antibody, p45 antibody, p45/SUG antibody, wu:fa14g03 antibody, wu:fb23a11 antibody, zgc:92464 antibody, sug-1 antibody, sug1 antibody, tbp10 antibody, Sug1 antibody, PSMC5 antibody, xsug1 antibody, protease (prosome, macropain) 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 L homeolog antibody, proteasome 26S subunit, ATPase 5 S homeolog antibody, Psmc5 antibody, PSMC5 antibody, psmc5 antibody, psmc5.L antibody, psmc5.S antibody
    背景
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.

    Cellular Localization: Cytoplasm (Potential) , Nucleus
    分子量
    46 kDa
    基因ID
    5705
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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