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BPNT1 抗体

BPNT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856006
发货至: 中国
  • 抗原 See all BPNT1 抗体
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This BPNT1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1)
    BPNT1 antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product BPNT1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse liver , HeLaS3

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.7 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    别名
    3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1 产品)
    别名
    BPNT1 antibody, PIP antibody, Sal3 antibody, BPntase antibody, 3'(2'), 5'-bisphosphate nucleotidase 1 antibody, bisphosphate 3'-nucleotidase 1 antibody, BPNT1 antibody, bpnt1.L antibody, Bpnt1 antibody
    背景
    BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

    分子量
    33 kDa
    基因ID
    10380
    UniProt
    O95861
    途径
    Inositol Metabolic Process
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