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HLA-DPA1 抗体

HLA-DPA1 适用: 人 WB, IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855822
发货至: 中国
  • 抗原 See all HLA-DPA1 抗体
    HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
    适用
    • 37
    • 1
    • 1
    宿主
    • 34
    • 3
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This HLA-DPA1 antibody is un-conjugated
    应用范围
    • 28
    • 22
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)
    HLA-DPA1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human HLA-DPA1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product HLA-DPA1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
    别名
    major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1 产品)
    别名
    DP(W3) antibody, DP(W4) antibody, HLA-DP1A antibody, HLADP antibody, HLASB antibody, PLT1 antibody, major histocompatibility complex, class II, DP alpha 1 antibody, HLA-DPA1 antibody
    背景
    HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    29 kDa
    基因ID
    3113
    UniProt
    P20036
    途径
    TCR Signaling, Cancer Immune Checkpoints
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