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HSD17B4 抗体

HSD17B4 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855717
发货至: 中国
  • 抗原 See all HSD17B4 抗体
    HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
    适用
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    宿主
    • 55
    • 3
    克隆类型
    • 55
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    多克隆
    标记
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    This HSD17B4 antibody is un-conjugated
    应用范围
    • 50
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    人, 大鼠
    产品特性
    Rabbit Polyclonal antibody to HSD17B4 (hydroxysteroid (17-beta) dehydrogenase 4)
    HSD17B4 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human HSD17B4. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Rat heart

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Frasinyuk, Zhang, Wyrebek, Yu, Xu, Sviripa, Bondarenko, Xie, Ngo, Morris, Mohler, Fiandalo, Watt, Liu: "Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." in: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).

  • 抗原
    HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
    别名
    hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4 产品)
    别名
    zgc:55545 antibody, zgc:77300 antibody, CG3415 antibody, DmMFE-2 antibody, Dmel\\CG3415 antibody, MFE-2 antibody, DBP antibody, MPF-2 antibody, PRLTS1 antibody, SDR8C1 antibody, 17-beta-HSD antibody, 17[b]-HSD antibody, 4 antibody, MFP2 antibody, Mfp-2 antibody, perMFE-2 antibody, hydroxysteroid (17-beta) dehydrogenase 4 antibody, hydroxysteroid 17-beta dehydrogenase 4 antibody, peroxisomal Multifunctional enzyme type 2 antibody, hsd17b4 antibody, HSD17B4 antibody, Mfe2 antibody, Hsd17b4 antibody
    背景
    The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8.

    Cellular Localization: Peroxisome
    分子量
    80 kDa
    基因ID
    3295
    UniProt
    P51659
    途径
    Monocarboxylic Acid Catabolic Process
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