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Kallikrein 7 抗体

KLK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855653
发货至: 中国
  • 抗原 See all Kallikrein 7 (KLK7) 抗体
    Kallikrein 7 (KLK7)
    适用
    • 43
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    宿主
    • 71
    • 6
    克隆类型
    • 74
    • 3
    多克隆
    标记
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    This Kallikrein 7 antibody is un-conjugated
    应用范围
    • 48
    • 30
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    • 13
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    • 7
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to KLK7 (kallikrein-related peptidase 7)
    KLK7 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Kallikrein 7. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product KLK7 Primary Antibody
  • 应用备注
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Kallikrein 7-transfected 293T

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.69 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." in: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

  • 抗原
    Kallikrein 7 (KLK7)
    别名
    kallikrein related peptidase 7 (KLK7 产品)
    别名
    Prss6 antibody, SCCE antibody, PRSS6 antibody, hK7 antibody, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antibody, kallikrein-related peptidase 7 antibody, kallikrein related peptidase 7 antibody, Klk7 antibody, KLK7 antibody
    背景
    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.

    Cellular Localization: Secreted
    分子量
    28 kDa
    基因ID
    5650
    UniProt
    P49862
    途径
    Complement System
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