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KLF5 抗体

KO Validated KLF5 适用: 人 WB, IP, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855604
发货至: 中国
  • 抗原 See all KLF5 抗体
    KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))
    适用
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    宿主
    • 68
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    克隆类型
    • 70
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    多克隆
    标记
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    This KLF5 antibody is un-conjugated
    应用范围
    • 45
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    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to KLF5 (Kruppel-like factor 5 (intestinal))
    KLF5 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human KLF5. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product KLF5 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: KLF5-transfected 293T , HeLa (500 μM CoCl2 treatment for 24 hr and 10 μM MG132 treatment for 2 hr)

    Validation: KO/KD, Orthogonal, Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.8 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Sun, Li, Wang, Yue, Bai, Bian, Hao, Sun, Zhang, Liu: "Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration." in: Cell death & disease, Vol. 11, Issue 6, pp. 432, (2020) (PubMed).

    Ma, Chang, Zhao, Zhao, Xiong, Cao, Yuan, Zhang, Wang, Geng, Zheng, Li: "KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression." in: Scientific reports, Vol. 7, Issue 1, pp. 15683, (2019) (PubMed).

  • 抗原
    KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))
    别名
    Kruppel like factor 5 (KLF5 产品)
    别名
    KLF5 antibody, klf5 antibody, MGC115081 antibody, BTEB2 antibody, Bteb2 antibody, IKLF antibody, bteb2 antibody, 4930520J07Rik antibody, CKLF antibody, Kruppel like factor 5 antibody, Kruppel-like factor 5 (intestinal) S homeolog antibody, Kruppel-like factor 5 antibody, KLF5 antibody, klf5.S antibody, Klf5 antibody
    背景
    This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

    Cellular Localization: Nucleus
    分子量
    51 kDa
    基因ID
    688
    UniProt
    Q13887
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