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CD13 抗体

ANPEP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855482
发货至: 中国
  • 抗原 See all CD13 (ANPEP) 抗体
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    适用
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    克隆类型
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    多克隆
    标记
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    This CD13 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to CD13 (alanyl (membrane) aminopeptidase)
    CD13 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human CD13. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ANPEP Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: THP-1 , HL-60 , ANPEP-transfected 293T

    Validation: Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.82 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    别名
    alanyl aminopeptidase, membrane (ANPEP 产品)
    别名
    APN antibody, CD13 antibody, GP150 antibody, LAP1 antibody, P150 antibody, PEPN antibody, A2AP antibody, AAP antibody, ALPHA-2-PI antibody, API antibody, PLI antibody, AAT1 antibody, ALT1 antibody, GPT1 antibody, Gpt1 antibody, Apn antibody, pepN antibody, SC8E4A.13 antibody, 1300007J06Rik antibody, 2310022B03Rik antibody, ALT antibody, Gpt-1 antibody, AP-M antibody, AP-N antibody, Cd13 antibody, Apm antibody, KZP antibody, Lap1 antibody, rAPN antibody, APDE antibody, p150 antibody, anpep antibody, fb64c05 antibody, wu:fb64c05 antibody, zgc:136771 antibody, alanyl aminopeptidase, membrane antibody, serpin family F member 2 antibody, glutamic--pyruvic transaminase antibody, aminopeptidase N antibody, aminopeptidase antibody, aminopeptidase n antibody, glutamic pyruvic transaminase, soluble antibody, alanyl (membrane) aminopeptidase antibody, membrane alanyl aminopeptidase antibody, alanyl (membrane) aminopeptidase b antibody, alanyl aminopeptidase, membrane L homeolog antibody, ANPEP antibody, SERPINF2 antibody, GPT antibody, Gpt antibody, Apn2 antibody, Apn1 antibody, SCO2643 antibody, pepN antibody, Shewana3_0897 antibody, Alvin_1024 antibody, Ndas_3413 antibody, Saut_1544 antibody, Fbal_1877 antibody, ML5_3424 antibody, Despr_1988 antibody, Mesop_5365 antibody, Anpep antibody, LOC101744250 antibody, anpepb antibody, anpep.L antibody
    背景
    Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

    Cellular Localization: Cell membrane, Single-pass type II membrane protein , Cytoplasm , cytosol , Cell membrane , Cytoplasm , cytosol
    分子量
    110 kDa
    基因ID
    290
    UniProt
    P15144
    途径
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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