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KAP1 抗体

TRIM28 适用: 人 WB, IF, IP, IHC (p), ICC, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855331
发货至: 中国
  • 抗原 See all KAP1 (TRIM28) 抗体
    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
    适用
    • 113
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    宿主
    • 114
    • 15
    • 4
    克隆类型
    • 107
    • 26
    多克隆
    标记
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    This KAP1 antibody is un-conjugated
    应用范围
    • 85
    • 42
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    • 27
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to KAP1 (tripartite motif containing 28)
    KAP1 antibody [N3C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human KAP1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product TRIM28 Primary Antibody
  • 应用备注
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: NIH-3T3

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.48 mg/mL
    缓冲液
    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liu, Li, Liu, Li, Wei, Liu, Lv: "Expression and Significance of TRIM 28 in Squamous Carcinoma of Esophagus." in: Pathology oncology research : POR, Vol. 25, Issue 4, pp. 1645-1652, (2020) (PubMed).

    Hung, Johnson, Chen, Byrum, Bredemeyer, Yewdell, Johnson, Lee, Deivasigamani, Hindi, Amatya, Gross, Paull, Pisapia, Chaudhuri, Petrini, Mosammaparast, Amarasinghe, Zha, Tyler, Sleckman: "MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining." in: Molecular cell, Vol. 71, Issue 2, pp. 332-342.e8, (2019) (PubMed).

    Wang, Wolgemuth: "BET Protein BRDT Complexes With HDAC1, PRMT5, and TRIM28 and Functions in Transcriptional Repression During Spermatogenesis." in: Journal of cellular biochemistry, Vol. 117, Issue 6, pp. 1429-38, (2016) (PubMed).

    Aslanian, Yates, Hunter: "Mass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cells." in: DNA repair, Vol. 15, pp. 29-38, (2014) (PubMed).

  • 抗原
    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
    别名
    tripartite motif containing 28 (TRIM28 产品)
    别名
    KAP1 antibody, RNF96 antibody, TF1B antibody, TIF1B antibody, TRIM28 antibody, kap1 antibody, rnf96 antibody, tf1b antibody, tif1b antibody, AA408787 antibody, KAP-1 antibody, KRIP-1 antibody, Tif1b antibody, Tif1beta antibody, Kap1 antibody, Krip1 antibody, TIF1BETA antibody, tripartite motif containing 28 antibody, tripartite motif containing 28 L homeolog antibody, tripartite motif-containing 28 antibody, TRIM28 antibody, trim28.L antibody, Trim28 antibody
    背景
    The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.

    Cellular Localization: Nucleus (By similarity)
    分子量
    89 kDa
    基因ID
    10155
    UniProt
    Q13263
    途径
    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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