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PSMA7 抗体 (Center)

PSMA7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855151
发货至: 中国
  • 抗原 See all PSMA7 抗体
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    抗原表位
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 43
    • 26
    • 18
    • 1
    人, 小鼠
    宿主
    • 37
    • 6
    克隆类型
    • 38
    • 5
    多克隆
    标记
    • 21
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMA7 antibody is un-conjugated
    应用范围
    • 40
    • 14
    • 14
    • 13
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鸡, 猪, 大鼠, 牛, Xenopus tropicalis
    交叉反应 (详细)
    Chicken (96 %), Pig (98 %), Rat (98 %), Bovine (99 %), Xenopus tropicalis (97 %)
    产品特性
    Rabbit Polyclonal antibody to PSMA7 (proteasome (prosome, macropain) subunit, alpha type, 7)
    PSMA7 antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Proteasome 20S alpha 7. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PSMA7 Primary Antibody
  • 应用备注
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.32 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    别名
    PSMA7 (PSMA7 产品)
    别名
    C6 antibody, HSPC antibody, RC6-1 antibody, XAPC7 antibody, C6-I antibody, DDBDRAFT_0185059 antibody, DDBDRAFT_0217080 antibody, DDB_0185059 antibody, DDB_0217080 antibody, hspc antibody, rc6-1 antibody, xapc7 antibody, psma7 antibody, psma4-B antibody, proteasome subunit alpha 7 antibody, proteasome (prosome, macropain) subunit, alpha type 7 antibody, 20S proteasome subunit alpha-7 antibody, proteasome subunit alpha 7 S homeolog antibody, proteasome subunit alpha 7 L homeolog antibody, PSMA7 antibody, Psma7 antibody, psmA7 antibody, psma7 antibody, psma7.S antibody, psma7.L antibody
    背景
    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9.

    Cellular Localization: Cytoplasm , Nucleus
    分子量
    28 kDa
    基因ID
    5688
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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