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BCL6 抗体 (Internal Region)

BCL6 适用: 人, 小鼠 WB, IHC (p), IP, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855012
发货至: 中国
  • 抗原 See all BCL6 抗体
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    抗原表位
    • 28
    • 22
    • 15
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Internal Region
    适用
    • 140
    • 71
    • 26
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 89
    • 51
    • 1
    克隆类型
    • 78
    • 63
    多克隆
    标记
    • 67
    • 13
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL6 antibody is un-conjugated
    应用范围
    • 89
    • 46
    • 34
    • 33
    • 33
    • 16
    • 16
    • 13
    • 13
    • 11
    • 5
    • 5
    • 5
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    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)
    产品特性
    Rabbit Polyclonal antibody to BCL6 (B-cell CLL/lymphoma 6)
    BCL6 antibody [N2C1], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human BCL6. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product BCL6 Primary Antibody
  • 应用备注
    Suggested dilution Reference ChIP assay Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceChIP assayAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
    说明

    Positive Control: Jurkat , Raji , NCI-H929 , Neuro2A , GL261 , C8D30 , NIH-3T3 , Raw264.7 , C2C12

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    别名
    BCL6 (BCL6 产品)
    别名
    bcl5 antibody, laz3 antibody, bcl6a antibody, znf51 antibody, zbtb27 antibody, MGC132260 antibody, Bcl5 antibody, BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, B-cell CLL/lymphoma 6 L homeolog antibody, B-cell CLL/lymphoma 6 antibody, B cell leukemia/lymphoma 6 antibody, bcl6.L antibody, bcl6 antibody, BCL6 antibody, Bcl6 antibody
    背景
    The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

    Cellular Localization: Nucleus
    分子量
    79 kDa
    基因ID
    604
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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