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BID 抗体

KO Validated BID 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855009
发货至: 中国
  • 抗原 See all BID 抗体
    BID (BH3 Interacting Domain Death Agonist (BID))
    适用
    • 124
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    宿主
    • 134
    • 19
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    • 2
    克隆类型
    • 125
    • 31
    多克隆
    标记
    • 86
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    • 3
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    This BID antibody is un-conjugated
    应用范围
    • 139
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    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    IP/MS validation was supported by references (PMID:30377376)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to Bid (BH3 interacting domain death agonist)
    Bid antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Bid. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product BID Primary Antibody
  • 应用备注
    WB: 1:1000-1:10000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: A431 , 293T

    Validation: IP/MS, KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.8 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    BID (BH3 Interacting Domain Death Agonist (BID))
    别名
    BH3 interacting domain death agonist (BID 产品)
    别名
    FP497 antibody, 2700049M22Rik antibody, AI875481 antibody, AU022477 antibody, BID antibody, bid antibody, si:ch211-238n5.6 antibody, fp497 antibody, xbid antibody, DKFZp469E066 antibody, BH3 interacting domain death agonist antibody, BH3 interacting domain death agonist S homeolog antibody, BID antibody, Bid antibody, bida antibody, bid.S antibody, bid antibody
    背景
    This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

    Cellular Localization: Cytoplasm , Mitochondrion membrane , BH3-interacting domain death agonist p15: Mitochondrion membrane , BH3-interacting domain death agonist p13: Mitochondrion membrane , Isoform 1: Cytoplasm , Isoform 3: Cytoplasm , Isoform 2: Mitochondrion membrane
    分子量
    22 kDa
    基因ID
    637
    UniProt
    P55957
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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