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MTDH 抗体

MTDH 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854801
发货至: 中国
  • 抗原 See all MTDH 抗体
    MTDH (Metadherin (MTDH))
    适用
    • 53
    • 18
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 8
    • 3
    克隆类型
    • 45
    • 9
    多克隆
    标记
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTDH antibody is un-conjugated
    应用范围
    • 44
    • 15
    • 13
    • 13
    • 11
    • 11
    • 10
    • 9
    • 8
    • 6
    • 4
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit polyclonal antibody to LYRIC (metadherin)
    LYRIC antibody [N2C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human LYRIC . The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: rat brain

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.69 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lai, Chuang, Liu, Ho, Lin, Anderson, Yeh: "Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection." in: Scientific reports, Vol. 7, Issue 1, pp. 6975, (2019) (PubMed).

  • 抗原
    MTDH (Metadherin (MTDH))
    别名
    metadherin (MTDH 产品)
    别名
    MGC75963 antibody, 2610103J23Rik antibody, 3D3 antibody, 3D3/Lyric antibody, AEG-1 antibody, AV353288 antibody, D8Bwg1112e antibody, Lyric antibody, AEG1 antibody, LYRIC antibody, LYRIC/3D3 antibody, metadherin antibody, mtdh antibody, MTDH antibody, Mtdh antibody
    背景
    Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

    Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein (By similarity) , Cell junction , tight junction (By similarity) , Nucleus , nucleolus (By similarity) , Cytoplasm , perinuclear region
    分子量
    64 kDa
    基因ID
    92140
    UniProt
    Q86UE4
    途径
    Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
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