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MMP1 抗体

MMP1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854783
发货至: 中国
  • 抗原 See all MMP1 抗体
    MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This MMP1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to MMP1 (matrix metallopeptidase 1 (interstitial collagenase))
    MMP1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human MMP1. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.7 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Bordignon, Bottoni, Xu, Popescu, Truan, Guenova, Kofler, Jafari, Ostano, Röcken, Neel, Dotto: "Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant." in: Cell reports, Vol. 28, Issue 9, pp. 2358-2372.e6, (2020) (PubMed).

    Wu, Lin, Hou, Chang, Wen, Lin, Chiang: "1,2-Bis[(3-Methoxyphenyl)Methyl]Ethane-1,2-Dicarboxylic Acid Reduces UVB-Induced Photodamage In Vitro and In Vivo." in: Antioxidants (Basel, Switzerland), Vol. 8, Issue 10, (2019) (PubMed).

    Dubey, Wei, Yu, Williams, Wang, Deng, Tsai, Wang, Deng: "Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade." in: Aging and disease, Vol. 10, Issue 3, pp. 483-496, (2019) (PubMed).

    Olaya-C, Garrido, Hernandez-Losa, Sesé, Ayala-Ramirez, Somoza, Vargas, Ramón Y Cajal: "The umbilical cord, preeclampsia and the VEGF family." in: International journal of women's health, Vol. 10, pp. 783-795, (2018) (PubMed).

    Kim, Choi, Lee, Soh, Kim, Park: "Senescent tumor cells lead the collective invasion in thyroid cancer." in: Nature communications, Vol. 8, pp. 15208, (2018) (PubMed).

  • 抗原
    MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
    别名
    matrix metallopeptidase 1 (MMP1 产品)
    别名
    CLG antibody, CLGN antibody, Mmp1a antibody, CG4859 antibody, Dm1-MMP antibody, Dmel\\CG4859 antibody, MMP-1 antibody, MMP1 antibody, Mmp 1 antibody, dMMP1 antibody, dm1-MMP antibody, dmmp1 antibody, l(2)k04809 antibody, mmp1 antibody, Mmp1 antibody, Mcol-A antibody, Mcola antibody, col4 antibody, mmp18 antibody, Clgn antibody, matrix metallopeptidase 1 antibody, Matrix metalloproteinase 1 antibody, matrix metalloproteinase 1 antibody, matrix metallopeptidase 1 (interstitial collagenase) antibody, matrix metallopeptidase 1a (interstitial collagenase) antibody, matrix metallopeptidase 1 S homeolog antibody, interstitial collagenase antibody, matrix metallopeptidase 8 L homeolog antibody, MMP1 antibody, Mmp1 antibody, RB11133 antibody, Mmp1a antibody, mmp1.S antibody, LOC100727966 antibody, mmp8.L antibody
    背景
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    分子量
    54 kDa
    基因ID
    4312
    UniProt
    P03956
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