TYMS 抗体 (C-Term)
(2 references)-
- 抗原 See all TYMS 抗体
- TYMS (Thymidylate Synthetase (TYMS))
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抗原表位
- AA 265-294, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TYMS antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TYSY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human TYSY.
- 克隆位点
- RB20041
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TYMS Primary Antibody
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anti-Thymidylate Synthetase (TYMS) (AA 36-313) antibody
TYMS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 60-174) antibodyTYMS 适用: 人 WB, IF, FACS, IHC, ISt, RIA, StM 宿主: 小鼠 Monoclonal TYMS-1884 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 111-210) antibodyTYMS 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5H8 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 111-210) antibodyTYMS 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 2B2 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 265-294), (C-Term) antibodyTYMS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20041 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 2-54) antibodyTYMS 适用: 人 WB, IF, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF: 1:50. IF: 1:50. WB: 1:2000. IHC-P: 1:500. IHC-P: 1:500. FC: 1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Comparative analysis of thymidylate synthase at the protein, mRNA, and DNA levels as prognostic markers in colorectal adenocarcinoma." in: Journal of surgical oncology, Vol. 100, Issue 7, pp. 546-52, (2009) (PubMed).
: "Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site." in: Biochemistry, Vol. 34, Issue 50, pp. 16279-87, (1996) (PubMed).
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: "Comparative analysis of thymidylate synthase at the protein, mRNA, and DNA levels as prognostic markers in colorectal adenocarcinoma." in: Journal of surgical oncology, Vol. 100, Issue 7, pp. 546-52, (2009) (PubMed).
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- 抗原
- TYMS (Thymidylate Synthetase (TYMS))
- Abstract
- TYMS 产品
- 别名
- FN1 antibody, ECK2823 antibody, JW2795 antibody, ts antibody, Ts antibody, HST422 antibody, TMS antibody, TS antibody, thymidylate synthetase antibody, contains intron in T4 phage antibody, ThyE antibody, thymidylate synthase antibody, thymidylate synthetase L homeolog antibody, TYMS antibody, thyA antibody, td antibody, thyE antibody, DDA3937_RS04960 antibody, tyms.L antibody, XBJ1_RS15770 antibody, EAMY_RS20680 antibody, Tyms antibody
- 背景
- Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.
- 分子量
- 35716
- NCBI登录号
- NP_001062
- UniProt
- P04818
- 途径
- Mitotic G1-G1/S Phases
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