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HBV PreS1,PreS2 抗体 (Alexa Fluor 594)

HBV PreS1,PreS2 适用: Virus WB 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2814166
发货至: 中国
  • 抗原 See all HBV PreS1,PreS2 products
    HBV PreS1,PreS2 (Hepatitis B Virus PreS1/PreS2 Protein (HBV PreS1,PreS2))
    适用
    • 17
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    Virus
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
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    This HBV PreS1,PreS2 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 19
    • 3
    Western Blotting (WB)
    交叉反应
    Virus
    交叉反应 (详细)
    Hepatitis B virus ay/ad
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from HBSAG_HBVD2 sub. ayw pre S1/S2 protein
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HBV PreS1,PreS2 (Hepatitis B Virus PreS1/PreS2 Protein (HBV PreS1,PreS2))
    别名
    HBV Pre S1/ S2 Protein (HBV PreS1,PreS2 产品)
    物质类
    Viral Protein
    背景

    Synonyms: Hepatitis B, HBSAG_HBVD2, HBSAG_HBVC5, Large envelope protein, Large surface protein, L glycoprotein, Major surface antigen, Large S protein, L-HBsAg, LHB

    Background: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.

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