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GCNT7 抗体 (AA 241-430) (Alexa Fluor 594)

GCNT7 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2813647
发货至: 中国
  • 抗原 See all GCNT7 抗体
    GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))
    抗原表位
    • 14
    • 9
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 241-430
    适用
    • 35
    • 4
    • 3
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GCNT7 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 35
    • 19
    • 12
    • 12
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GCNT7
    亚型
    IgG
    Top Product
    Discover our top product GCNT7 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))
    别名
    GCNT7 (GCNT7 产品)
    别名
    A330041C17Rik antibody, gnt antibody, C20orf105 antibody, dJ1153D9.2 antibody, gcnt antibody, C17H20orf105 antibody, glucosaminyl (N-acetyl) transferase family member 7 antibody, Gcnt7 antibody, GCNT7 antibody
    背景

    Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 7, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, C20orf105, GCNT, GCNT7, GCNT7_HUMAN, glucosaminyl N-acetyl transferase family member 7.

    Background: Belonging to the glycosyltransferase 14 family, GCNT7, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus. Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6. GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins. Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologies involving Selectin proteins.

    基因ID
    140687
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