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EMP1 抗体 (AA 101-160) (Alexa Fluor 594)

EMP1 适用: 人, 小鼠, 大鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2812776
发货至: 中国
  • 抗原 See all EMP1 products
    EMP1 (Epithelial Membrane Protein 1 (EMP1))
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 101-160
    适用
    人, 小鼠, 大鼠
    宿主
    • 33
    • 1
    克隆类型
    • 34
    多克隆
    标记
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EMP1 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 19
    • 15
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse Emp1
    亚型
    IgG
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    EMP1 (Epithelial Membrane Protein 1 (EMP1))
    别名
    EMP1 (EMP1 产品)
    别名
    MGC84779 antibody, EMP1 antibody, si:ch73-90k17.2 antibody, CL-20 antibody, EMP-1 antibody, TMP antibody, I-8-09 antibody, ENP1MR antibody, epithelial membrane protein 1 antibody, epithelial membrane protein 1 L homeolog antibody, EMP1 antibody, emp1.L antibody, emp1 antibody, Emp1 antibody
    背景

    Synonyms: TMP, I-8-9, Epithelial membrane protein 1, EMP-1, Tumor-associated membrane protein, Emp1

    Background: Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.

    基因ID
    13730
    UniProt
    P47801
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