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CBLN4 抗体 (AA 101-201) (Alexa Fluor 594)

CBLN4 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2811182
发货至: 中国
  • 抗原 See all CBLN4 抗体
    CBLN4 (Cerebellin 4 Precursor (CBLN4))
    抗原表位
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-201
    适用
    • 31
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 30
    • 1
    克隆类型
    • 31
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CBLN4 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 23
    • 12
    • 12
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CBLN4
    亚型
    IgG
    Top Product
    Discover our top product CBLN4 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CBLN4 (Cerebellin 4 Precursor (CBLN4))
    别名
    CBLN4 (CBLN4 产品)
    别名
    zgc:172190 antibody, cerebellin-4 antibody, CBLNL1 antibody, AI848962 antibody, cerebellin 4 precursor antibody, cerebellin 4 precursor L homeolog antibody, cerebellin 4 precursor protein antibody, CBLN4 antibody, cbln4 antibody, cbln4.L antibody, Cbln4 antibody
    背景

    Synonyms: CBLN 4, CBLNL1, Cerebellin 4, Cerebellin 4 precursor, Cerebellin like glycoprotein 1, Cerebellin precursor like 1, Cerebellin4, CBLN4_HUMAN.

    Background: Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other?s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of Cerebellin have been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for Cerebellin in the pathology of these diseases.

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