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Phospholipase C gamma 1 抗体

PLCG1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1944927
发货至: 中国
  • 抗原 See all Phospholipase C gamma 1 (PLCG1) 抗体
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    适用
    • 152
    • 137
    • 127
    • 23
    • 9
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 161
    • 23
    克隆类型
    • 145
    • 39
    多克隆
    标记
    • 87
    • 11
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    This Phospholipase C gamma 1 antibody is un-conjugated
    应用范围
    • 122
    • 53
    • 38
    • 31
    • 28
    • 27
    • 19
    • 17
    • 15
    • 13
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    亚型
    IgG
    Top Product
    Discover our top product PLCG1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC: 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C,-20 °C
  • Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

    Park, Min, Rhee: "Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1." in: The Journal of biological chemistry, Vol. 267, Issue 3, pp. 1496-501, (1992) (PubMed).

    Mohammadi, Honegger, Rotin, Fischer, Bellot, Li, Dionne, Jaye, Rubinstein, Schlessinger: "A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1." in: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5068-78, (1991) (PubMed).

    Burgess, Dionne, Kaplow, Mudd, Friesel, Zilberstein, Schlessinger, Jaye: "Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase." in: Molecular and cellular biology, Vol. 10, Issue 9, pp. 4770-7, (1990) (PubMed).

  • 抗原
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    别名
    PLCG1 (PLCG1 产品)
    别名
    NCKAP3 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, PLCgamma1 antibody, plc1 antibody, nckap3 antibody, plc-ii antibody, plc148 antibody, plcgamma1 antibody, PPLCA antibody, AI894140 antibody, Cded antibody, Plc-1 antibody, Plc-gamma1 antibody, Plcg-1 antibody, fj46f04 antibody, wu:fj46f04 antibody, wu:fj57a05 antibody, phospholipase C gamma 1 antibody, phospholipase C gamma 1 L homeolog antibody, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antibody, phospholipase C, gamma 1 antibody, PLCG1 antibody, plcg1.L antibody, LOC100633163 antibody, Plcg1 antibody, plcg1 antibody
    背景
    Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
    分子量
    148532 Da
    基因ID
    5335
    UniProt
    P19174
    途径
    RTK signaling, WNT signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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