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PTPN11 抗体

PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1944921
发货至: 中国
  • 抗原 See all PTPN11 抗体
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    适用
    • 157
    • 116
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    • 10
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    人, 小鼠, 大鼠
    宿主
    • 172
    • 14
    • 2
    • 1
    克隆类型
    • 152
    • 37
    多克隆
    标记
    • 88
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    This PTPN11 antibody is un-conjugated
    应用范围
    • 124
    • 53
    • 42
    • 27
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    Western Blotting (WB), Immunohistochemistry (IHC)
    亚型
    IgG
    Top Product
    Discover our top product PTPN11 Primary Antibody
  • 应用备注
    WB: 1:500-1:1000. WB: 1:500-1:1000. IHC: 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C,-20 °C
  • Adachi, Sekiya, Miyachi, Matsuno, Hinoda, Imai, Yachi: "Molecular cloning of a novel protein-tyrosine phosphatase SH-PTP3 with sequence similarity to the src-homology region 2." in: FEBS letters, Vol. 314, Issue 3, pp. 335-9, (1993) (PubMed).

    Freeman, Plutzky, Neel: "Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 23, pp. 11239-43, (1993) (PubMed).

    Bastien, Ramachandran, Liu, Adam: "Cloning, expression and mutational analysis of SH-PTP2, human protein-tyrosine phosphatase." in: Biochemical and biophysical research communications, Vol. 196, Issue 1, pp. 124-33, (1993) (PubMed).

    Ahmad, Banville, Zhao, Fischer, Shen: "A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 6, pp. 2197-201, (1993) (PubMed).

    Vogel, Lammers, Huang, Ullrich: "Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation." in: Science (New York, N.Y.), Vol. 259, Issue 5101, pp. 1611-4, (1993) (PubMed).

  • 抗原
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    别名
    SH-PTP2 (PTPN11 产品)
    别名
    BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
    物质类
    Viral Protein
    背景
    Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
    分子量
    68436 Da
    基因ID
    5781
    UniProt
    Q06124
    途径
    JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect
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