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TCEB1 抗体 (N-Term)

TCEB1 适用: 人, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792679
发货至: 中国
  • 抗原 See all TCEB1 抗体
    TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 54
    • 15
    • 14
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 犬, 斑马鱼
    宿主
    • 50
    • 3
    • 1
    克隆类型
    • 54
    多克隆
    标记
    • 25
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TCEB1 antibody is un-conjugated
    应用范围
    • 33
    • 26
    • 25
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    EHALTSGTIK AMLSGPGQFA ENETNEVNFR EIPSHVLSKV CMYFTYKVRY
    交叉反应
    牛, 犬, 小鸡, 人, 小鼠, 大鼠
    预测反应
    Dog: 100%, Human: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against TCEB1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TCEB1
    Top Product
    Discover our top product TCEB1 Primary Antibody
  • 应用备注
    WB Suggested Anti-TCEB1 Antibody Titration: 0.2-1 µg/mL
    Positive Control: Raji cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 112 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
    别名
    TCEB1 (TCEB1 产品)
    别名
    2610043E24Rik antibody, 2610301I15Rik antibody, AA407206 antibody, AI987979 antibody, AW049146 antibody, SIII antibody, eloC antibody, TCEB1 antibody, fb09f09 antibody, wu:fb09f09 antibody, zgc:111990 antibody, zgc:92635 antibody, elongin C antibody, elongin C L homeolog antibody, transcription elongation factor B (SIII), polypeptide 1b antibody, Eloc antibody, eloc.L antibody, ELOC antibody, tceb1b antibody
    背景
    TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    Alias Symbols: SIII, eloC
    Protein Interaction Partner: UBC, TCEB2, FUS, vif, METTL21C, SOCS4, CUL5, PRAME, POP1, MDM2, VHL, ASB18, ASB12, ASB14, ASB15, ASB9, ASB8, ASB7, ASB5, ASB10, ASB16, ASB13, ASB1, ASB3, APEX1, CUL2, Zswim8, ASB2, CPTP, CBX5, MRAS, JTB, RCAN2, SOCS1, CUL3, WNT7B, NEDD8, HIF1A, EFNB3, CYP
    Protein Size: 112
    分子量
    12 kDa
    基因ID
    6921
    NCBI登录号
    NM_005648, NP_005639
    UniProt
    Q15369
    途径
    SARS-CoV-2 Protein Interactome
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