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YWHAE 抗体 (Middle Region)

YWHAE 适用: 小鼠, 斑马鱼, 豚鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792142
发货至: 中国
  • 抗原 See all YWHAE 抗体
    YWHAE (14-3-3 epsilon (YWHAE))
    抗原表位
    • 15
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 52
    • 37
    • 34
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠, 斑马鱼, 豚鼠, 犬
    宿主
    • 48
    • 4
    • 1
    克隆类型
    • 41
    • 12
    多克隆
    标记
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This YWHAE antibody is un-conjugated
    应用范围
    • 41
    • 17
    • 13
    • 13
    • 13
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    ELDTLSEESY KDSTLIMQLL RDNLTLWTSD MQGDGEEQNK EALQDVEDEN
    预测反应
    Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against YWHAE. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human YWHAE
    Top Product
    Discover our top product YWHAE Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 255 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tak, Jang, Kim, Park, Suk, Yoon, Ahn, Lee, Joe: "14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization." in: Cellular signalling, Vol. 19, Issue 11, pp. 2379-87, (2007) (PubMed).

  • 抗原
    YWHAE (14-3-3 epsilon (YWHAE))
    别名
    YWHAE (YWHAE 产品)
    别名
    14-3-3 antibody, 14-3-3 epsilon antibody, 14-3-3-e antibody, 14-3-3-epsilon antibody, 14-3-30epsilon antibody, 14-3-3EPSILON antibody, 14-3-3e antibody, 14-3-3omicron antibody, 1433epsilon antibody, 143E_DROME antibody, CG31196 antibody, CT24092 antibody, D14-3-3e antibody, D14-3-3epsilon antibody, Dmel\\CG31196 antibody, EK3-5 antibody, PAR-5 antibody, PAR5 antibody, Par-5 antibody, SR3-9 antibody, Su(Raf)3B antibody, anon-WO0172774.141 antibody, anon-WO02059370.52 antibody, d14-3-3epsilon antibody, eps antibody, l(3)j2B10 antibody, par-5 antibody, 14-3-3epsilon antibody, kcip-1 antibody, mdcr antibody, mds antibody, LOC581376 antibody, Ywhae antibody, ACYPI002517 antibody, YWHAE antibody, 14-3-3E antibody, KCIP-1 antibody, MDCR antibody, MDS antibody, AU019196 antibody, fe38c12 antibody, wu:fb48f06 antibody, wu:fe38c12 antibody, wu:fi22e10 antibody, ywhae antibody, zgc:55377 antibody, zgc:77062 antibody, CG31196 gene product from transcript CG31196-RD antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon antibody, 14-3-3 epsilon antibody, 14-3-3 epsilon protein antibody, 14-3-3 protein epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 antibody, 14-3-3epsilon antibody, ywhae antibody, LOC581376 antibody, Ywhae antibody, HCAG_04173 antibody, PTRG_02836 antibody, PTRG_04459 antibody, UREG_07864 antibody, YWHAE antibody, ywhae.S antibody, ywhae1 antibody
    背景
    YWHAE is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAE binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. The binding generally results in the modulation of the activity of the binding partner.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: 14-3-3E, FLJ45465, KCIP-1, MDCR, MDS
    Protein Interaction Partner: DTL, HUWE1, FAM53C, FBXW11, SORBS2, UBC, ABL1, GRB10, SIK2, CEP57, SIK3, TP53, IRS4, CBL, TUBB2A, TWF2, PROSC, FERMT2, PDIA4, RAP1GDS1, PTMA, PPP1R2, PDHB, PAK2, PAFAH1B2, YWHAH, XPO1, VCL, GSS, G6PD, EIF5, TBCB, CAPNS1, CAPN2, ALDH7A1, ATIC, ASNS, SCPEP1
    Protein Size: 255
    分子量
    29 kDa
    基因ID
    7531
    NCBI登录号
    NM_006761, NP_006752
    UniProt
    P62258
    途径
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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