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- 抗原 See all TNFSF14 抗体
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
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抗原表位
- Middle Region
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适用
- 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFSF14 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ATSSSRVWWD SSFLGGVVHL EAGEKVVVRV LDERLVRLRD GTRSYFGAFM
- 预测反应
- Dog: 92%
- 产品特性
- This is a rabbit polyclonal antibody against TNFSF14. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TNFSF14
- Top Product
- Discover our top product TNFSF14 Primary Antibody
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 62-240) antibody
TNFSF14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 61-170) antibodyTNFSF14 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 4E3 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 141-240) antibodyTNFSF14 适用: 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 51-239) antibodyTNFSF14 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 62-240) antibodyTNFSF14 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239) antibodyTNFSF14 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (Internal Region) antibodyVerified TNFSF14 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 58-239) antibodyTNFSF14 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-204) antibodyTNFSF14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 240 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- 别名
- TNFSF14 (TNFSF14 产品)
- 别名
- TNFSF14 antibody, CD258 antibody, HVEML antibody, LIGHT antibody, LTg antibody, TR2 antibody, HVEM-L antibody, Ly113 antibody, TNF superfamily member 14 antibody, tumor necrosis factor (ligand) superfamily, member 14 antibody, TNFSF14 antibody, Tnfsf14 antibody
- 背景
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TNFSF14 is the cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B TNFSF14 modulates its effects. TNFSF14 activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. TNFSF14 acts as a receptor for Herpes simplex virus.The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Alias Symbols: CD258, HVEML, LIGHT, LTg, TR2
Protein Interaction Partner: APP, TNFRSF6B, TNFRSF14, LTBR, LTB, DIABLO, TRAF3, TRAF2, BIRC2,
Protein Size: 240 - 分子量
- 22 kDa
- 基因ID
- 8740
- NCBI登录号
- NM_003807, NP_003798
- UniProt
- O43557
- 途径
- Cancer Immune Checkpoints
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