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Histone 3 抗体 (N-Term)

The 兔 多克隆 anti-Histone 3 antibody (ABIN786552) specifically detects Histone 3 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN786552
发货至: 中国
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Quick Overview for Histone 3 抗体 (N-Term) (ABIN786552)

抗原

See all Histone 3 (H3) 抗体
Histone 3 (H3) (Histone H3 (H3))

适用

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宿主

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克隆类型

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多克隆

标记

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This Histone 3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MARTKQTARK STGGKAPRKQ LATKVARKSA PATGGVKKPH RYRPGTVALR

    产品特性

    This is a rabbit polyclonal antibody against HIST3H3. It was validated on Western Blot.

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HIST3H3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 136 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Histone 3 (H3) (Histone H3 (H3))

    别名

    HIST3H3

    背景

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
    Alias Symbols: H3.4, H3/g, H3FT, H3t, MGC126886, MGC126888
    Protein Interaction Partner: RAD6, SETD7, WHSC1L1, PRDM2, WHSC1, KMT2A, PHF7, CBX5, TRIM28, ING2, UBC, K07C5.3, APLF, UHRF1, NEDD8, CUL4A, EZH2, ASF1B, ASF1A, MMS22L, IGSF8, TONSL, ICAM1, CD81, AURKA, MLLT1, TAF8, TAF3, TAF9B, PHF21A, ING4, PRAME, KAT6B, CBX6, PHF8, PHF2, ITGA4, TAF1
    Protein Size: 136

    分子量

    15 kDa

    基因ID

    8290

    NCBI登录号

    NM_003493, NP_003484

    UniProt

    P84243
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