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MYSM1 抗体 (N-Term)

MYSM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2790658
发货至: 中国
  • 抗原 See all MYSM1 抗体
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 35
    • 18
    • 1
    • 1
    • 1
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYSM1 antibody is un-conjugated
    应用范围
    • 22
    • 21
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    KLIGSRTVLQ VKSYARQYFK NKVKCGLDKE TPNQKTGHNL QVKNEDKGTK
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against MYSM1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human MYSM1
    Top Product
    Discover our top product MYSM1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 828 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    别名
    MYSM1 (MYSM1 产品)
    背景
    MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
    Alias Symbols: 2A-DUB, 2ADUB, DKFZp779J1554, DKFZp779J1721, KIAA1915, RP4-592A1.1
    Protein Interaction Partner: UBC, DICER1, SUMO2, TUBB1, WDR77, STK38, PRMT5, KAT2B, HIST2H2AC, RBM10, KIF11, HSPA1A, HNRNPH1, EEF1A1,
    Protein Size: 828
    分子量
    91 kDa
    基因ID
    114803
    NCBI登录号
    NM_001085487, NP_001078956
    UniProt
    Q5VVJ2
    途径
    Chromatin Binding
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