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- 抗原 See all KIR2DL1 抗体
- KIR2DL1 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIR2DL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 序列
- DEQDPQEVTY TQLNHCVFTQ RKITRPSQRP KTPPTDIIVY TELPNAESRS
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KIR2DL1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product KIR2DL1 Primary Antibody
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anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 162-267) antibody
KIR2DL1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) antibodyKIR2DL1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 23-223) antibodyKIR2DL1 适用: 人 WB, ELISA, FACS, ICC, IF 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) antibodyKIR2DL1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) antibodyKIR2DL1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 1-374) antibodyKIR2DL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 1-374) antibodyKIR2DL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (C-Term) antibodyKIR2DL1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1) (AA 22-348) antibodyKIR2DL1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 348 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- KIR2DL1 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
- 别名
- KIR2DL1 (KIR2DL1 产品)
- 别名
- NKAT antibody, NKAT1 antibody, p58.1 antibody, CD158A antibody, KIR221 antibody, KIR-K64 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 antibody, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 antibody, KIR2DL1 antibody
- 背景
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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Alias Symbols: CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1
Protein Interaction Partner: HLA-C,
Protein Size: 348 - 分子量
- 38 kDa
- 基因ID
- 3802
- NCBI登录号
- NM_014218, NP_055033
- UniProt
- P43626
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