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HLA-E 抗体 (Middle Region)

HLA-E 适用: 人, Pig, 山羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789267
发货至: 中国
  • 抗原 See all HLA-E 抗体
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    抗原表位
    • 16
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 66
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, Pig, 山羊
    宿主
    • 43
    • 24
    克隆类型
    • 45
    • 22
    多克隆
    标记
    • 30
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-E antibody is un-conjugated
    应用范围
    • 41
    • 27
    • 19
    • 13
    • 13
    • 12
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DTAAQISEQK SNDASEAEHQ RAYLEDTCVE WLHKYLEKGK ETLLHLEPPK
    预测反应
    Goat: 83%, Human: 100%, Pig: 93%
    产品特性
    This is a rabbit polyclonal antibody against HLA-E. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product HLA-E Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 358 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    别名
    HLA-E (HLA-E 产品)
    背景
    HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
    Alias Symbols: DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1
    Protein Interaction Partner: UBC, CALR, TAP2, UBD, PPP1R16A, KLRD1, KLRC2, CD8A, KLRC1, HLA-E, B2M,
    Protein Size: 358
    分子量
    38 kDa
    基因ID
    3133
    NCBI登录号
    NM_005516, NP_005507
    UniProt
    P13747
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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