AKR1C3 抗体 (N-Term)
-
- 抗原 See all AKR1C3 抗体
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
-
抗原表位
- N-Term
- 适用
- 人, 兔, 大鼠, 小鼠, Cow, Pig, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This AKR1C3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- PALENSLKKA QLDYVDLYLI HSPMSLKPGE ELSPTDENGK VIFDIVDLCT
- 预测反应
- Cow: 85%, Guinea Pig: 85%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 86%, Rat: 85%
- 产品特性
- This is a rabbit polyclonal antibody against AKR1C3. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product AKR1C3 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 323 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
- 别名
- AKR1C3 (AKR1C3 产品)
- 别名
- AKR1C3 antibody, PGFS antibody, MGC134333 antibody, DD3 antibody, DDX antibody, HA1753 antibody, HAKRB antibody, HAKRe antibody, HSD17B5 antibody, hluPGFS antibody, Akr1c18 antibody, aldo-keto reductase family 1, member C3 L homeolog antibody, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1 member C3 antibody, aldo-keto reductase family 1, member C3 antibody, akr1c3.L antibody, AKR1C3 antibody, LOC722496 antibody, Akr1c3 antibody
- 背景
-
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS
Protein Interaction Partner: UBC, LRIF1, ZHX1, UBE2W, ACIN1, MAGEA11,
Protein Size: 323 - 分子量
- 36 kDa
- 基因ID
- 8644
- NCBI登录号
- NM_003739, NP_003730
- UniProt
- P42330
- 途径
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
-