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CYP3A5 抗体 (N-Term)

CYP3A5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788347
发货至: 中国
  • 抗原 See all CYP3A5 抗体
    CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
    抗原表位
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 绵羊
    宿主
    • 20
    • 3
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP3A5 antibody is un-conjugated
    应用范围
    • 16
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    AITDPDVIRT VLVKECYSVF TNRRSLGPVG FMKSAISLAE DEEWKRIRSL
    预测反应
    Cow: 79%, Dog: 91%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 79%, Sheep: 79%
    产品特性
    This is a rabbit polyclonal antibody against CYP3A5. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CYP3A5
    Top Product
    Discover our top product CYP3A5 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 502 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
    别名
    CYP3A5 (CYP3A5 产品)
    背景
    This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene.
    Alias Symbols: CP35, P450PCN3, PCN3, CYPIIIA5
    Protein Interaction Partner: RDH13, ATOH8, ETV5,
    Protein Size: 502
    分子量
    57 kDa
    基因ID
    1577
    NCBI登录号
    NM_000777, NP_000768
    UniProt
    P51589
    途径
    Steroid Hormone Biosynthesis
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