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RAGE 抗体 (N-Term)

AGER 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786877
发货至: 中国
  • 抗原 See all RAGE (AGER) 抗体
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    抗原表位
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    N-Term
    适用
    • 148
    • 82
    • 64
    • 8
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    • 3
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    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马
    宿主
    • 142
    • 11
    • 4
    • 2
    • 1
    克隆类型
    • 136
    • 23
    • 1
    多克隆
    标记
    • 71
    • 12
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    • 6
    • 3
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    This RAGE antibody is un-conjugated
    应用范围
    • 127
    • 71
    • 54
    • 34
    • 27
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    • 24
    • 11
    • 8
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    • 3
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    Western Blotting (WB)
    序列
    MKQRFESIEQ VNNLREIQAL RRLNPHPNIL MLHEVVFDRK SGSLALICEL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against RAGE. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human RAGE
    Top Product
    Discover our top product AGER Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 419 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tafani, Schito, Pellegrini, Villanova, Marfe, Anwar, Rosa, Indelicato, Fini, Pucci, Russo: "Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B." in: Carcinogenesis, Vol. 32, Issue 8, pp. 1167-75, (2011) (PubMed).

  • 抗原
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    别名
    RAGE (AGER 产品)
    背景
    RAGE is able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
    Alias Symbols: MOK, RAGE1, RAGE, RAGE-1
    Protein Interaction Partner: UBC, WDR18, SDF4, HUWE1, ZNF223, MOK, INSR, MAPK6, MYC, JUN, CCNB1,
    Protein Size: 419
    分子量
    48 kDa
    基因ID
    5891
    NCBI登录号
    NM_013401, NP_055041
    UniProt
    Q9UQ07
    途径
    Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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