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ARG2 抗体 (C-Term)

ARG2 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785775
发货至: 中国
  • 抗原 See all ARG2 抗体
    ARG2 (Arginase, Type II (ARG2))
    抗原表位
    • 19
    • 15
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 50
    • 34
    • 15
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠
    宿主
    • 57
    • 11
    克隆类型
    • 60
    • 8
    多克隆
    标记
    • 36
    • 11
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARG2 antibody is un-conjugated
    应用范围
    • 62
    • 22
    • 21
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 6
    • 4
    Western Blotting (WB)
    序列
    SALDLVEVNP QLATSEEEAK TTANLAVDVI ASSFGQTREG GHIVYDQLPT
    交叉反应
    牛, 犬, 人, 小鼠, 兔, 大鼠
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 87%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against ARG2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human ARG2
    Top Product
    Discover our top product ARG2 Primary Antibody
  • 应用备注
    WB Suggested Anti-ARG2 Antibody Titration: 0.2-1 µg/mL
    Positive Control: Jurkat cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 354 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lukasova, Malaval, Gille, Kero, Offermanns: "Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells." in: The Journal of clinical investigation, Vol. 121, Issue 3, pp. 1163-73, (2011) (PubMed).

  • 抗原
    ARG2 (Arginase, Type II (ARG2))
    别名
    Arginase-2 (ARG2 产品)
    别名
    AII antibody, AU022422 antibody, zgc:65793 antibody, zgc:85630 antibody, wu:fb67g02 antibody, ARG2 antibody, LeARG2 antibody, arg1 antibody, arg3 antibody, arg2 antibody, arg2-c antibody, arg2-b antibody, arginase 2 antibody, arginase type II antibody, arginase 2 L homeolog antibody, arginase 2 S homeolog antibody, ARG2 antibody, Arg2 antibody, arg2 antibody, arg2.L antibody, arg2.S antibody
    背景
    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. ARG2 (type II isoform) is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: UBC, ARG1,
    Protein Size: 354
    分子量
    39 kDa
    基因ID
    384
    NCBI登录号
    NM_001172, NP_001163
    UniProt
    P78540
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