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ERCC5 抗体 (N-Term)

ERCC5 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785635
发货至: 中国
  • 抗原 See all ERCC5 抗体
    ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
    抗原表位
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 45
    • 12
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠
    宿主
    • 41
    • 4
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERCC5 antibody is un-conjugated
    应用范围
    • 34
    • 19
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    HSGHIRRQYE DEGGFLKEVE SRRVVSEDTS HYILIKGIQA KTVAEVDSES
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against ERCC5. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human ERCC5
    Top Product
    Discover our top product ERCC5 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
    别名
    ERCC5 (ERCC5 产品)
    别名
    COFS3 antibody, ERCM2 antibody, UVDR antibody, XPG antibody, XPGC antibody, cofs3 antibody, ercm2 antibody, uvdr antibody, xpg antibody, xpgc antibody, Xpg antibody, ERCC excision repair 5, endonuclease antibody, excision repair cross-complementation group 5 L homeolog antibody, excision repair cross-complementing rodent repair deficiency, complementation group 5 antibody, ERCC5 antibody, ercc5.L antibody, Ercc5 antibody
    背景
    This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.
    Protein Interaction Partner: UBC, CDK7, GTF2H1, POLR2A, EWSR1, ERCC6, SUMO2, PIDD1, BCL6, TAF10, ERCC3, NTHL1, GTF2H4, PCNA, ERCC2,
    Protein Size: 1180
    分子量
    130 kDa
    基因ID
    2073
    UniProt
    P28715
    途径
    DNA Damage Repair
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