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ACVR1C/ALK7 抗体 (N-Term)

ACVR1C 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785115
发货至: 中国
  • 抗原 See all ACVR1C/ALK7 (ACVR1C) 抗体
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    抗原表位
    • 16
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 44
    • 42
    • 28
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, Pig, 犬, 兔, 豚鼠, 马
    宿主
    • 53
    • 5
    克隆类型
    • 55
    • 3
    多克隆
    标记
    • 28
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACVR1C/ALK7 antibody is un-conjugated
    应用范围
    • 50
    • 25
    • 20
    • 13
    • 13
    • 11
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    QVFCHSSNNV TKTECCFTDF CNNITLHLPT ASPNAPKLGP MELAIIITVP
    预测反应
    Cow: 100%, Dog: 83%, Guinea Pig: 80%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 81%, Rabbit: 100%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against ACVR1C. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1C
    Top Product
    Discover our top product ACVR1C Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 493 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    别名
    ACVR1C (ACVR1C 产品)
    别名
    ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody
    背景
    ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
    Alias Symbols: ACVRLK7, ALK7
    Protein Interaction Partner: HSP90AA1, TDGF1, INHBB,
    Protein Size: 493
    分子量
    55 kDa
    基因ID
    130399
    NCBI登录号
    NM_145259, NP_660302
    UniProt
    Q8NER5
    途径
    Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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