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CYP27A1 抗体 (Middle Region)

CYP27A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784620
发货至: 中国
  • 抗原 See all CYP27A1 抗体
    CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 37
    • 32
    • 11
    • 1
    宿主
    • 50
    • 2
    克隆类型
    • 43
    • 9
    多克隆
    标记
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP27A1 antibody is un-conjugated
    应用范围
    • 33
    • 14
    • 14
    • 13
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    SRDPTAFSEP ESFQPHRWLR NSQPATPRIQ HPFGSVPFGY GVRACLGRRI
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against CYP27A1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CYP27A1
    Top Product
    Discover our top product CYP27A1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 531 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Szlago, Gallus, Schenone, Patiño, Sfaelo, Rufa, Da Pozzo, Cardaioli, Dotti, Federico: "The first cerebrotendinous xanthomatosis family from Argentina: a new mutation in CYP27A1 gene." in: Neurology, Vol. 70, Issue 5, pp. 402-4, (2008) (PubMed).

  • 抗原
    CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
    别名
    CYP27A1 (CYP27A1 产品)
    别名
    CP27 antibody, CTX antibody, CYP27 antibody, Cyp27 antibody, P450C27 antibody, 1300013A03Rik antibody, cytochrome P450 family 27 subfamily A member 1 antibody, cytochrome P450, family 27, subfamily a, polypeptide 1 antibody, cytochrome P450, family 27, subfamily A, polypeptide 1 antibody, sterol 26-hydroxylase, mitochondrial antibody, CYP27A1 antibody, Cyp27a1 antibody, cyp27a1 antibody
    背景
    CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CP27, CTX, CYP27
    Protein Interaction Partner: PRDX4,
    Protein Size: 531
    分子量
    57 kDa
    基因ID
    1593
    NCBI登录号
    NM_000784, NP_000775
    UniProt
    Q02318
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