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MBNL2 抗体 (Middle Region)

MBNL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784554
发货至: 中国
  • 抗原 See all MBNL2 抗体
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    抗原表位
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 23
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马
    宿主
    • 22
    • 1
    克隆类型
    • 22
    • 1
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This MBNL2 antibody is un-conjugated
    应用范围
    • 20
    • 14
    • 14
    • 13
    • 4
    • 1
    Western Blotting (WB)
    序列
    ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against MBNL2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MBNL2
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 255 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    别名
    MBNL2 (MBNL2 产品)
    别名
    1110002M11Rik antibody, AI047808 antibody, AI837313 antibody, AI849185 antibody, AL118326 antibody, MBLL antibody, R75232 antibody, mKIAA4072 antibody, wu:fj89c04 antibody, MBLL39 antibody, PRO2032 antibody, muscleblind like splicing factor 2 antibody, muscleblind-like splicing regulator 2 antibody, muscleblind like splicing regulator 2 antibody, Mbnl2 antibody, mbnl2 antibody, MBNL2 antibody
    背景
    MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
    Alias Symbols: DKFZp781H1296, MBLL, MBLL39, MGC120625, MGC120626, MGC120628, PRO2032, RP11-128N14.1
    Protein Interaction Partner: BMI1, ELAVL1, UBC,
    Protein Size: 255
    分子量
    28 kDa
    基因ID
    10150
    NCBI登录号
    NM_005757, NP_005748
    UniProt
    O95205
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