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SIN3B 抗体 (Middle Region)

SIN3B 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784242
发货至: 中国
  • 抗原 See all SIN3B 抗体
    SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 35
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 豚鼠, 兔
    宿主
    • 33
    • 4
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIN3B antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 12
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    NDTKALRSKS LLNEIESVYD EHQEQHSEGR SAPSSEPHLI FVYEDRQILE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against SIN3B. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SIN3B
    Top Product
    Discover our top product SIN3B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1162 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Dhanda, Lindberg, Olsson: "The human SIN3B corepressor forms a nucleolar complex with leukemia-associated ETO homologues." in: BMC molecular biology, Vol. 9, pp. 8, (2008) (PubMed).

  • 抗原
    SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
    别名
    SIN3B (SIN3B 产品)
    别名
    fj63d08 antibody, si:dkey-6n6.6 antibody, wu:fj63d08 antibody, 2810430C10Rik antibody, SIN3 transcription regulator family member B antibody, SIN3 transcription regulator family member B S homeolog antibody, transcriptional regulator, SIN3B (yeast) antibody, sin3b antibody, SIN3B antibody, sin3b.S antibody, Sin3b antibody
    背景
    SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.
    Alias Symbols: KIAA0700
    Protein Interaction Partner: SOX2, HDAC1, HDAC2, UBC, ESR1, AR, TFAP4, TP53, SUMO2, KLF16, MORF4L1, MORF4L2, MRGBP, KDM5A, CIITA, NR1D2, COPS2, SMN1, PBX1, REST, ZBTB4, ARID4A, MYT1, MXI1, SAP25, SMARCE1, SMARCB1, SMARCA4, SMARCA2, CBFA2T3, RNF220, ZBTB16, SETDB1, HDAC9, IKZF4, IKZF1
    Protein Size: 1162
    分子量
    133 kDa
    基因ID
    23309
    NCBI登录号
    NM_015260, NP_056075
    UniProt
    O75182
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