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SPRY2 抗体 (N-Term)

SPRY2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784217
发货至: 中国
  • 抗原 See all SPRY2 抗体
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 37
    • 18
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 豚鼠
    宿主
    • 37
    • 3
    • 1
    • 1
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    This SPRY2 antibody is un-conjugated
    应用范围
    • 34
    • 25
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MEARAQSGNG SQPLLQTPRD GGRQRGEPDP RDALTQQVHV LSLDQIRAIR
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against SPRY2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SPRY2
    Top Product
    Discover our top product SPRY2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 315 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hsu, Lee, Hartstein, Harocopos: "Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." in: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).

  • 抗原
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    别名
    SPRY2 (SPRY2 产品)
    别名
    wu:fk66h11 antibody, wu:fk93e11 antibody, zgc:110440 antibody, hspry2 antibody, xspry2 antibody, sprouty2 antibody, Xsprouty2 antibody, sprouty-2 antibody, Xtsprouty2 antibody, hSPRY2 antibody, sprouty RTK signaling antagonist 2 antibody, sprouty RTK signaling antagonist 2 S homeolog antibody, sprouty homolog 2 (Drosophila) antibody, spry2 antibody, SPRY2 antibody, spry2.S antibody, Spry2 antibody
    背景
    SPRY2 is a protein belonging to the sprouty family. It contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. SPRY2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. SPRY2 may play a role in alveoli branching during lung development as shown by a similar mouse protein.This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC23039, hSPRY2
    Protein Interaction Partner: PTGER3, PRKAB2, KRTAP4-11, ATRIP, KRTAP5-6, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, LCE3E, KRTAP5-9, GP9, OTX1, MLLT6, MEOX2, MDFI, LASP1, LCE2D, LCE1B, RUNX1T1, AQP1, LCE3C, LCE4A, ZNF417, HEXIM2, CATSPER1, LONRF1, KRTAP4-7, KR
    Protein Size: 315
    分子量
    35 kDa
    基因ID
    10253
    NCBI登录号
    NM_005842, NP_005833
    UniProt
    O43597
    途径
    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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