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- 抗原 See all HLA-DPA1 抗体
- HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
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抗原表位
- Middle Region
- 适用
- 人, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DPA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EAQEPIQMPE TTETVLCALG LVLGLVGIIV GTVLIIKSLR SGHDPRAQGT
- 预测反应
- Human: 100%, Pig: 86%
- 产品特性
- This is a rabbit polyclonal antibody against HLA-DPA1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HLA-DPA1
- Top Product
- Discover our top product HLA-DPA1 Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) (AA 1-260) antibody
HLA-DPA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) (AA 1-260) antibodyHLA-DPA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) antibodyHLA-DPA1 适用: 人 WB, IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) (AA 29-222) antibodyHLA-DPA1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) antibodyHLA-DPA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) (AA 1-260) antibodyHLA-DPA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) (N-Term) antibodyHLA-DPA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) antibody (HRP)HLA-DPA1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) antibody (Biotin)HLA-DPA1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1) antibody (FITC)HLA-DPA1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 260 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
- 别名
- HLA-DPA1 (HLA-DPA1 产品)
- 别名
- DP(W3) antibody, DP(W4) antibody, HLA-DP1A antibody, HLADP antibody, HLASB antibody, PLT1 antibody, major histocompatibility complex, class II, DP alpha 1 antibody, HLA-DPA1 antibody
- 背景
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The specific function of this protein remains unknown.HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HLA-DP1A, HLADP, HLASB, PLT1, DP(W3), DP(W4)
Protein Interaction Partner: UBC, CD4, HLA-DPB1, CD74,
Protein Size: 260 - 分子量
- 26 kDa
- 基因ID
- 3113
- NCBI登录号
- NM_033554, NP_291032
- UniProt
- P20036
- 途径
- TCR Signaling, Cancer Immune Checkpoints
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