ATP6V0A1 抗体 (N-Term)
(2 references)-
- 抗原 See all ATP6V0A1 抗体
- ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP6V0A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RDLNPDVNVF QRKFVNEVRR CEEMDRKLRF VEKEIRKANI PIMDTGENPE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ATP6V0A1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V0A1
- Top Product
- Discover our top product ATP6V0A1 Primary Antibody
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anti-ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1) (C-Term) antibody
ATP6V0A1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1) (AA 212-298) antibodyATP6V0A1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1) (AA 671-720) antibodyATP6V0A1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 831 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons." in: Cell death & disease, Vol. 9, Issue 6, pp. 626, (2019) (PubMed).
: "POLR2F, ATP6V0A1 and PRNP expression in colorectal cancer: new molecules with prognostic significance?" in: Anticancer research, Vol. 28, Issue 2B, pp. 1221-7, (2008) (PubMed).
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: "ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons." in: Cell death & disease, Vol. 9, Issue 6, pp. 626, (2019) (PubMed).
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- 抗原
- ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
- 别名
- ATP6V0A1 (ATP6V0A1 产品)
- 别名
- ATP6N1 antibody, ATP6N1A antibody, Stv1 antibody, VPP1 antibody, Vph1 antibody, a1 antibody, AA959968 antibody, ATP6a1 antibody, Atp6n1 antibody, Atp6n1a antibody, Atpv0a1 antibody, Vpp-1 antibody, Vpp1 antibody, A1 antibody, wu:fj37e01 antibody, zgc:112214 antibody, atp6v0a1 antibody, wu:fc25b09 antibody, zgc:76965 antibody, ATPase H+ transporting V0 subunit a1 antibody, ATPase, H+ transporting, lysosomal V0 subunit A1 antibody, si:ch73-173p19.2 antibody, ATPase, H+ transporting, lysosomal V0 subunit a1 L homeolog antibody, ATPase, H+ transporting, lysosomal V0 subunit a1b antibody, ATPase, H+ transporting, lysosomal V0 subunit a1a antibody, ATP6V0A1 antibody, Atp6v0a1 antibody, si:ch73-173p19.2 antibody, atp6v0a1.L antibody, atp6v0a1b antibody, atp6v0a1a antibody
- 背景
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ATP6V0A1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. ATP6V0A1 is one of three A subunit proteins and it is associated with clathrin-coated vesicles. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATP6N1, ATP6N1A, DKFZp781J1951, Stv1, VPP1, Vph1, a1
Protein Interaction Partner: SEH1L, ZNF267, SNX4, UBC, CLIC1, MARCKSL1, MRPL44, SLC30A5, MRPL50, PTRH2, ATP6V1D, MRPL46, SCFD1, VAMP2, SRSF3, RPS18, RPS15, SLC25A3, PA2G4, NONO, ATP6V1E1, ATP6V1B1,
Protein Size: 831 - 分子量
- 96 kDa
- 基因ID
- 535
- NCBI登录号
- NM_005177, NP_005168
- UniProt
- Q93050
- 途径
- Transition Metal Ion Homeostasis, Proton Transport
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