RFC3 抗体 (C-Term)
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- 抗原 See all RFC3 抗体
- RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 豚鼠, 兔, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IIMKGLLSEL LHNCDGQLKG EVAQMAAYYE HRLQLGSKAI YHLEAFVAKF
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against RFC3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RFC3
- Top Product
- Discover our top product RFC3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 356 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors." in: PLoS biology, Vol. 5, Issue 5, pp. e109, (2007) (PubMed).
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Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors." in: PLoS biology, Vol. 5, Issue 5, pp. e109, (2007) (PubMed).
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- 抗原
- RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
- 别名
- RFC3 (RFC3 产品)
- 别名
- CG5313 antibody, DRFC antibody, DmRFC3 antibody, Dmel\\CG5313 antibody, Rfc3 antibody, 21.m02902 antibody, 2810416I22Rik antibody, 38kDa antibody, AU022547 antibody, Recc3 antibody, cb275 antibody, RFC38 antibody, Replication factor C subunit 3 antibody, replication factor C3 antibody, replication factor C subunit 3 antibody, replication factor C 38 kDa subunit antibody, DNA replication factor C complex subunit Rfc3 antibody, replication factor C3, putative antibody, replication factor C (activator 1) 3 antibody, replication factor C subunit 3 L homeolog antibody, RfC3 antibody, PF14_0601 antibody, Chro.30359 antibody, PB000006.01.0 antibody, PC000345.04.0 antibody, TP04_0380 antibody, Tb09.211.3310 antibody, PY04255 antibody, PVX_117300 antibody, BBOV_IV003080 antibody, SJAG_02182 antibody, PKH_124240 antibody, rfc3 antibody, Rfc3 antibody, RFC3 antibody, rfc3.L antibody
- 背景
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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: MGC5276, RFC38
Protein Interaction Partner: PCNA, TP53, UBC, RPA3, RPA2, RPA1, RPP40, FBXO6, ARFGAP1, VCP, RFC4, RFC5, RFC2, RFC1, PURB, PURA, MCM3, Cebpb, RAD21, HDGF, SMARCAD1, EBNA-LP, MESDC2, MYC, FAN1, MEPCE, USP20, CHTF8, RAD17, BRD4, CHTF18,
Protein Size: 356 - 分子量
- 40 kDa
- 基因ID
- 5983
- NCBI登录号
- NM_002915, NP_002906
- UniProt
- P40938
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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